Hereditary Glaucoma Affecting Three Generations

Hereditary Glaucoma Occurrence in Five Generations of an Edinburgh Family.

A REGULAR Mendelian dominant pattern of inheritance is characteristic of so-called juvenile glaucoma and some hundred genealogies have been recorded (Fran9ois, 1961), two-thirds showing one or two affected generations and the other third three to six generations. However, in a condition of such high prevalence as primary glaucoma, two successive affected generations are not sufficient to prove ...

Tonographic survey of the close relatives of patients with chronic simple glaucoma.

THAT glaucoma simplex may affect more than one member of a family is well known, but this would usually appear to occur in a sporadic fashion and have no hereditary significance. When true hereditary glaucoma occurs it is found in many members of the same family and is frequently traced over three or four generations. These families are, however, rare and have been well documented (Francois, 19...

Hereditary benign Telangiectasia: Report of 6 cases in a family

Hereditary benign telangiectasia is an uncommon idiopathic skin disorder characterized by generalized telangiectases and angiomatous lesions of the skin. The diagnosis should be suspected in patients with such cutaneous lesions, positive family history, no associated bleeding problems, and no mucosal involvement. We present six cases of hereditary benign telangiectasia in three generations of o...

Autosomal dominant juvenile onset glaucoma affecting six generations in an Edinburgh family.

Sulcus vocalis: evidence for autosomal dominant inheritance.

We found evidence of autosomal dominant hereditary transmission of sulcus vocalis. Four dysphonic patients from three generations of the same family were submitted to videolaryngoscopic examination (three patients) and to direct laryngoscopy (one patient) to diagnose the hoarseness. Sulcus vocalis was diagnosed in all four patients. The finding of four affected individuals in three generat...